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KMID : 0389520030100020108
Sleep Medicine.Psychophysiology
2003 Volume.10 No. 2 p.108 ~ p.112
Effects of Total Sleep Deprivation on Auditory Event-Related Potentials
Lee Heon-Jeong

Chun Ho-Seok
Kim Leen
Suh Kwang-Yoon
Abstract
Objectives: The purpose of this study is to investigate the psychophysiological effects of total sleep deprivation by using auditory event?related potentials.

Methods: Twenty four healthy college students (18 men, 6 women) participated in this study. The subjects remained awake for 37 hours under continuous surveillance. In the morning and the evening of two consecutive study days, auditory event?related potentials were checked.

Results: The latencies of P300 and N200 were significantly prolonged (p<0.001) and their amplitudes decreased (p<0.05) as a consequence of sleep deprivation. The amplitude of P200 was significantly increased during sleep deprivation (p(0.05). However, there was no significant change in the latency and amplitude of N100.

Conclusion: Among the components of auditory event?related potentials, P300 and N200 are good indicators of sleep?deprived status. Further investigation is necessary to elucidate the neurophysiological mechanisms of these findings. Sleep Medicine and Psshophysioiolb. 2003: 10(2) : 108-112
KEYWORD
Sleep deprivation, Auditory event-related potentials,
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